Gilbert announced she plans to depart the series on April 9.
The co-host and show creator made the announcement on Tuesday’s show.
Chen has moderated the popular daytime talk show since 2010.
Chen’s co-hosts spent the first part of the show addressing Moonves’ ouster.
Chen addressed the sexual misconduct allegations against Moonves on “The Talk.”
“I didn’t have anybody to really talk to,” she said.