“I, Spike Lee Of Sound Mind And Body Will No Longer Wear Prada Or Gucci,” he said.
“We believe that R. Kelly’s music should be banned on R&B radio stations.”
The comedy made $13.7 million at the weekend box office.
“OMG! Cancel your subscription,” someone tweeted.
His statement came after the group announced plans to join the #MuteRKelly campaign.